GERAINT WILLIAMS makes three changes to his side for Saturday's visit of Carlisle United, with two enforced by injury.
Jamie Jones and Ben Chorley both suffered knocks in the loss to Stoke City and Glenn Morris and Luke Ashworth come in for their first League starts of the season as a result.
Scott McGleish returns from a calf injury to partner Ryan Jarvis up front, while 17-year-old goalkeeper Jack Giddens, a second year scholar, is named as a substitute for the first time.
Leyton Orient: 1. Glenn Morris, 2. Stephen Purches (capt), 5. Tamika Mkandawire, 6. Luke Ashworth, 7. JJ Melligan, 9. Scott McGleish, 11. Jason Demetriou, 13. Charlie Daniels, 14. Ryan Jarvis, 20. Jimmy Smith, 25. Andros Townsend
Subs: 8. Adam Chambers, 16. Andrew Cave-Brown, 17. Loick Pires, 18. Harry Baker, 21. Matthew Hall, 23. Adrian Patulea, 26. Jack Giddens (GK)
Carlisle United: 40. Lenny Pidgeley, 2. David Raven, 5. Danny Livesey, 6. Peter Murphy, 7. Joe Anyinsah, 9. Scott Dobie, 10. Matt Robson, 11. Paul Thirlwell, 12. Tom Taiwo, 14. Ian Harte, 24. Kevan Hurst
Subs: 1. Adam Collin (GK), 3. Evan Horwood, 8. Graham Kavanagh, 15. Gavin Rothery, 17. Richard Offiong, 23. Tony Kane, 28. Gary Madine
Referee: Graham Horwood