Leyton Orient make the long trip to Carlisle United hoping to make it three wins on the spin.
Following on from the 1-0 win at Notts County, the O’s picked up their first home win in three attempts when defeating Crawley Town 2-0 on Saturday.
A double from Armand Gnanduillet was enough to seal all three points against the Reds and move Orient into the Play-Off places ahead of tonight’s match.
Carlisle United currently sit in 11th place in the League Two table going into the fixture, but are just three points behind Kevin Nolan’s side.
Keith Curle’s outfit came from behind on Saturday to secure a 2-1 win at Morecambe.
They trailed thanks to Kevin Ellison’s first half strike for the Shrimps, but two goals in as many minutes saw them pick up all three points.
Charlie Wyke slotted home an 83rd minute penalty before Derek Asamoah sealed victory for the Cumbrians.
THE LAST TIME AT BRUNTON PARK
Carlisle United 1
Leyton Orient 5
Sky Bet League One
The O’s enjoyed a fine start to the League One season as they enjoyed an emphatic opening day win at Brunton Park.
Kevin Lisbie put Orient in front after 22 minutes before the hosts saw Lee Miller shown a straight red card from referee Jeremy Simpson.
Scott Cuthbert extend the visitors lead, though the hosts pulled one back before the break when David Amoo slotted home a 43rd-minute penalty.
Russell Slade’s side restored their two-goal cushion with 20 minutes to go, before two strikes in the final 10 minutes from substitute Dean Cox saw Orient sail to victory.
ORIENT: Jones, Sawyer, Cuthbert, Clarke (Omozusi 33), Baudry, Odubajo, James, Vincelot, Batt (Cox 69), Lisbie (Gorman 83), Mooney
SUBS: Larkins, Vanderhyde, Lee, Bartley
GOALS: Lisbie (22), Cuthbert (37) Mooney (70), Cox (83 & 90)
Jobi McAnuff remains a doubt for the O’s after picking up an ankle injury in training late last week.
Fellow midfielder Lloyd James continues his recovery from an Achilles problem and is back training with the squad, however, tonight’s game has come too soon.
Dean Cox and Paul McCallum remain absentees, but are both well on their way in their recovery from knee ligament injuries.
BETTING (Sky Bet Odds correct at the time of preview)
Leyton Orient are 11/8 to pick up victory at Brunton Park this evening, with the draw at 23/10. Carlisle are available at 2/1.
Last time out at Brunton Park the O’s were 5-1 winners and for the same score tonight the odds are 150/1.
Former Orient favourite Jabo Ibehre is top of the goalscoring market for the hosts, priced at 5/1 to score first or 7/4 to score anytime, while Jay Simpson leads the way for Orient at 9/2 and 6/4.
Not able to make it today? Follow coverage of the game on the O’s official Twitter feed. If you are looking for audio coverage, you can listen to commentary from BBC London’s Mark Taylor on Orient PlayerHD.
Following the match head to leytonorient.com for match report and reaction.