Will Sanders struck late in the second-half to wrap up the three points for the youth team.
Orient got the game underway but after a matter of minutes Yeovil had a free-kick cleared off the line when the ball was drilled in and took a deflection goal-wards before last ditch defending kept the scores level early on.
The next attack fell in favour of this O’s, central defender Shadrach Ogie swung his left foot at Eric Lopes’ corner kick but the defender’s connection wasn’t firm enough to trouble to Yeovil ‘keeper as the ball bounced out for a goal kick.
Minutes later, Lopes was involved in a six-yard box tussle with a Yeovil forward but the referee and his assistant waved play-on as they saw no wrongdoing despite appeals from the travelling side.
Charles Clayden got the better of his man on the left wing and crossed a low ball in to the box where Jaedon Phillips waited to tap home, but for a last second challenge from a Yeovil defender to put the O’s forward off and win the ball back for the visitors.
As 20 minutes of play approached, Orient ‘keeper Sam Amedu was forced to save the ball with his legs when an attack down the left for the visitors saw a powerful shot fired towards goal after the midfielder made his way in to the box.
Opponents Yeovil were left to rue another missed chance when more good work from the left wing saw the ball dragged back to meet the late run of the visiting midfielder who then fired high and wide of the target with his first time shot.
On the 30-minute mark, Clayden found Phillips inside the box but the latter’s touch towards the ‘keeper lacked power and trickled in to the hands of the shot stopper in what was certainly a let off for Yeovil.
After an eventful first half an hour, meant the latter stages of the opening 45 came to a quieter close with Orient enjoying the majority of possession.
With just under 10 minutes of the second half played, Luca Carter-Henry was introduced in place of forward Ruel Sotiriou, this forced a formation change which saw Clayden move to partner Phillips on the front-line.
The majority of possession paid off when Orient took the lead on 75 minutes through Will Sanders’ glancing header passed the advancing Yeovil ‘keeper as the young defender connected with Amin Benyoucef’s free-kick.
The home side continued to dominate the ball but a rare Yeovil attack needed an acrobatic clearance from Andrew Camilo-Tayaca to clear the Orient defence of danger.
Orient held on to their lead in the final minutes of the game to record their fourth successive victory after a tough battle at home to Yeovil.
ORIENT: Samuel Amedu, Andrew Camilo-Tayaca, Eric Lopes (Alfie Fleming 66), Ernold Haxhiu, Will Sanders, Shadrach Ogie, Amin Benyoucef, Hector Kyprianou, Jaedon Phillips, Ruel Sotiriou (Luca Carter-Henry 54), Charles Clayden (Jeremie Sivi, 69)
SUBS: Bradley McClenaghan
GOAL: Sanders (75)