The National League leaders fell to only their second league defeat of the season last week as a 4th minute strike by Femi Ilesanmi saw a 1-0 defeat for the O’s.
The O’s reached the FA Trophy Fourth Round last season, beating Haringey Borough, Bognor Regis Town and Dover before a defeat to Gateshead stopped them reaching the Semi-Final.
Gary Meakin’s side currently sit in 7th position in the Evo-Stik Southern Premier South, having been promoted from the Southern Football League East Division last season.
They qualified for the First Round after defeating Leiston 3-1 with goals coming from Charlie Losasso, Jordan Ajanlekoko and Marvin Morgan.
The Rams secured a draw against Poole Town in their most recent fixture, Charlie Losasso’s goal just before half-time earnng a point.
The O’s are expected to make a couple of changes as Myles Judd will definitely miss the game while James Dayton is now a long-term absentee. Youngsters Arthur Janata and Hector Kyprianou cannot feature having been cup-tied while on loan while Charlie Lee may return to contention.
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Audio commentary will be available through the match centre which will appear at the top of the leytonorient.com homepage, with commentary starting 30 minutes before kick-off.
Match report and reaction following the game will appear on leytonorient.com.