After a third straight league win against Morecambe, The O's will continue their run of winning home games - and look to add another three points.
The fixtures are expected to be played on the following dates, although neither are confirmed.
Second Round – 16th September:
Plymouth Argyle (H)
Third Round – 23rd September:
Tottenham Hotspur (H)
The O’s beat Forest Green to progress from the First round thanks to goals from Danny Johnson and Conor Wilkinson: