The hosts, Carlisle United, will be keen to bounce back on Tuesday night, having suffered a 3-1 defeat to Stevenage at the weekend.
This fixture was postponed back in February because of a frozen pitch.
Carlisle currently sit 11th with 48 points, one point above Orient, however, The Cumbrians have a two-game advantage on the O’s.
In recent matches, Chris Beech’s side have struggled to find consistency – winning just one match in their last eleven.
Centre-back Rod McDonald will be missing for United, having picked up a red card against Stevenage.
Referee: JAMES BELL
Assistant Referees: Matthew Parry and Paul Graham
Fourth Official: Peter Wright
This is the first time Bell has officiated a Leyton Orient fixture. The referee has officiated 25 games so far this season, booking 71 players, sending-off seven and awarding eight spot-kicks.
A word from the Gaffer
Listen to Jobi McAnuff’s post-match interview, following Orient’s 1-0 win against Newport County.
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